Second only to calcium, phosphorous is the most plentiful mineral in your body, and it is necessary for such processes as the production and storage of energy. When you have too much potassium in your blood, it is called high potassium, or hyperkalemia. Severe arteriosclerosis (hardening of the arteries) can result, leading to strokes, heart attacks, and poor circulation. "The rate of chlorine kill is the same [with high phosphates], but the rate of growth can be slower with low phosphates. Thus, the phosphorus level rises in your blood, with multiple bad effects on your body. Controlling Phosphates in a Fish Aquarium . Phosphorus exists in three forms in nature: (i) White phosphorus used as firecrackers, (ii) red phosphorus used in matches, and (iii) black phosphorus obtained by phase transformation of white phosphorus or red phosphorous at high temperature and pressure. I am … Breathing in white phosphorus can cause you to cough or develop a condition known as phossy jaw that involves poor wound healing in the mouth and a breakdown of the jaw bone. Abnormally high or low levels may cause serious metabolic problems. We do not control or have responsibility for the content of any third-party site. ... (Largest Dialysis Organization in the U.S.) calls the mineral a "Silent Disease," that "can kill!" Two bad things happen from that combination. So on warm summer nights during algal blooms, the dissolved-oxygen concentration sometimes drops too low for the fish, and a die-off can occur.This can occur as a result of purely natural conditions or because of human activity that results in adding nutrients, nitrogen and phosphorus, to water systems.Nutrients come from many sources: fertilizers, automobiles, sewage, manure, and others. High phosphorus levels can also cause bone pain, muscle fatigue, and even heart problems. An excess of the mineral can cause diarrhea, as well as a hardening of organs and soft tissue. However, getting too much phosphorus can be … They provide phosphorus and water, as well as other nutrients to the plant. Here is a list of 17 foods high in phosphorus you should eat regularly to avoid phosphorus deficiency. It helps by getting to the root cause of the problem and allowing the body to naturally heal whatever is leading to the bleeding gums, chronic bloody nose, heavy menstrual flow, or even bleeding from the stomach lining. Its cosmic abundance is about one atom per 100 atoms of silicon, the standard. Crystals can also form in the skin, where they cause severe itching. It's a race of reproductive growth that is faster with more phosphates (up to a limit determined by sunlight and temperature) vs. killing by chlorine.” This explains why chlorine demand tends to be higher with high phosphate levels in a swimming pool. High phosphorous levels in your soil are usually the culprit of over-fertilizing or adding too much manure. Should I be worried? As we have learnt, the use of greywater with a high content of laundry detergent can be quite harmful to plants, causing phosphorus toxicity and sodium issues. I got my dogs blood work history from 6/2/18 for her insurance. Too much phosphorus can actually leach calcium from your bones, making them weak. As mentioned before, high phosphates in a pool can promote algae growth, leading to a green and cloudy pool. The Manual was first published as the Merck Manual in 1899 as a service to the community. Wave action and oceanic water currents return this inorganic phosphorus to the surface, where it can again be utilized by algae and other autotrophs. Chronically high phosphorus levels in the blood can impact health and life expectancy. Dialysis removes some phosphorus, but not as much as your kidneys would remove. First, as the calcium combines with the phosphorus, the calcium phosphate, which is essentially chalk, goes outside your blood system and hardens all the tissues it comes into contact with, such as your heart and your skin and muscles. Causes. It causes skin to melt away from the bone and can break down a victim's jawbone, but white phosphorus - known in Vietnam as Willie Pete - is still used by sections of the world's military. Which of the following is a cause of virilization that does not involve a tumor or cancer? Severe arteriosclerosis (hardening of the arteries) can result, leading to strokes, heart attacks, and poor circulation. Detergent can also affect the cycle which contains tripolyphosphate. High soil phospho-rus levels also can threaten streams, rivers, lakes and oceans. High phosphorus levels are also toxic to mycorrhizal fungi which are very important to landscape plants. In people with kidney dysfunction, hyperphosphatemia is treated by reducing consumption of phosphate and reducing absorption of phosphate from the digestive tract. The Manual was first published as the Merck Manual in 1899 as a service to the community. We want you to eat good amount of protein, but limit phosphorus intake. When you need additional phosphorus, use an organic source such as bone meal, soy meal, manure, or bat guano. When you have kidney disease, your kidneys cannot remove extra potassium in the right way, and too much potassium can stay in your blood. Merck and Co., Inc., Kenilworth, NJ, USA (known as MSD outside of the US and Canada) is a global healthcare leader working to help the world be well. East Clinic 4600 American Parkway Madison, WI 53718-8337 (608) 270-5600, Fitchburg Clinic 3034 Fish Hatchery Road Fitchburg, WI 53713 (608) 270-5600. Dialysis removes some phosphorus, but not as much as your kidneys would remove. This element is used in such processes as photosynthesis and energy transfer. Return to top. Plus, if your phosphorus is really high, we can't give you vitamin D you receive on dialysis (Zemplar) which you need to keep the PTH down and preserve your bones. Thus, the phosphorus level rises in your blood, with multiple bad effects on your body. If your body is unable to properly filter out and discard excess phosphorus, this could lead to a buildup. High potassium can even cause a heart attack or death! Although we are not in your shoes, we know how difficult it is to lie under the dietary restrictions of dialysis. Low phosphate levels in children can inhibit bone growth and high levels may be an indication of a condition that disrupts the body's balance of minerals. Chicken manure is high in Phosphorus and should be avoided on Phosphorus sensitive plants. If you take … For more information on keeping track of phosphorus in the foods you eat, recipes low in phosphorus, and cooking demonstrations for low-phosphorus recipes, visit Kidney Kitchen. Why can't I eat high phosphorus-containing foods? Fairclough says some people are more prone to the affects of a high salt diet. The diagnosis of hyperphosphatemia is based on blood tests indicating that the phosphate level is high. Second, you take "binders," which are pills which bind up the phosphorus in your food before your stomach can absorb it into your system. Its high chemical reactivity assures that it does not occur in the free state (except in a … If you have questions about controlling your phosphorus, please ask your dietitian, nurse or physician. But grass, just like every other plant, can’t grow without nitrates. , MD, Brookwood Baptist Health and Saint Vincent’s Ascension Health, Birmingham, (See also Overview of Electrolytes and Overview of Phosphate's Role in the Body.). Less commonly, hyperphosphatemia develops in people with the following: A low level of parathyroid hormone (hypoparathyroidism), Lack of response to a normal level of parathyroid hormone (pseudohypoparathyroidism), Destruction of muscle tissue (rhabdomyolysis), Large amounts of phosphate taken by mouth or given in an enema. Calciphylaxis is a condition that consists of painful sores on the skin that can … If you find that you have high phosphorus levels, try following some of the above tips to bring it under control. Q: The phosphorous level in my mother is very high.What should be done to reduce it? The foods you eat have a major impact on your body's ability, combined with dialysis and medications, to control sodium, potassium, phosphorous and protein. You Can have Too Much Compost. Risk of death increases at levels of phosphorus above 5.5 mg/dL. Without beneficial organisms, plants must put additional resources into root growth at the expense of other tissues and functions. Algae thrive when there is warm water, lots of sunlight, and a source of nitrogen and phosphorous. Too much phosphorus is typically caused by kidney disease, whereby the kidneys do not expel excess phosphorus. How do I keep my phosphorus below 5.5 mg/dl in my blood?First, the dietitians counsel you on a low phosphorus diet. Many annual bedding plants and newly planted perennial shrubs also can show symptoms. Identify and describe three human behaviors that impact the phosphorus cycle Humans can both raise livestock and use fertilizers which both can due to their waste, which is high in phosphorus which can both make its way to the soil. Hi. The trusted provider of medical information since 1899, Hypernatremia (High Level of Sodium in the Blood), Hyponatremia (Low Level of Sodium in the Blood), Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH), Hyperkalemia (High Level of Potassium in the Blood), Hypokalemia (Low Level of Potassium in the Blood), Hypercalcemia (High Level of Calcium in the Blood), Hypocalcemia (Low Level of Calcium in the Blood), Hypermagnesemia (High Level of Magnesium in the Blood), Hypomagnesemia (Low Level of Magnesium in the Blood), Hyperphosphatemia (High Level of Phosphate in the Blood), Hypophosphatemia (Low Level of Phosphate in the Blood). Reef Squad Emeritus . Also, high levels of phosphorus, either from chemical fertilizers or natural sources such as bone meal or rock phosphate, can inhibit growth of beneficial soil organisms called mycorrhizal fungi. If high potassium has symptoms, you may experience muscle weakness. If you control the phosphorus, the hardening of the arteries slows down or stops. Hyperphosphatemia is an electrolyte disturbance in which abnormally elevated levels of phosphate are present in the dog's blood. The normal amount of phosphorus in the blood (also called serum phosphorus) is between 2.5 – 4.5 mg/dL. The Phosphorus Cycle: Before the phosphorus can be used as nutrient for plants, we must wait for Mother Nature to perform its vital functions in order to take advantage of the raw materials that it offers.Phosphorus is an element classified as macro-nutrient since it directly participates - in large amounts - in the metabolism of all plants and especially in cannabis crops. High-phosphorus fertiliser will kill Grevillea moonlight Very short Very narrow Fast Aus Yes No All year No Yes Evergreen Remove lower branches as it grows to form tree. This is rare, however, and it is more common that high phosphorus levels lead to cardiovascular disease or osteoporosis. It can occur at any age but is more common in puppies or old dogs with kidney problems. In fact, new research shows that the way you cook your foods can make a difference too. This can occur as a result of purely natural conditions or because of human activity that results in adding nutrients, nitrogen and phosphorus, to water systems. Phosphorus is commonly used for: Anxiety and Fear: Phosphorus works quite well in curing anxiety and fear in and of itself. Your kidneys are the primary regulators of phosphorus balance in your body but many medical conditions can affect your phosphorus level. It is a key macronutrient that cannot be ignored if you want to grow strong and hearty plants and vegetables. The normal levels in blood are in the range 2.5-4.5 mg/dl. Iron deficiencies are characterized by yellowing between the leaf veins. What happens to my body if my phosphorus level is higher than 5.5 mg/dl?When the phosphorus level goes up, it combines with the calcium in your blood. The amount of phosphorus in these are ranked according to the content of phosphorus in 100 gram. Each ion has a … While rock phosphate is considered an organic source of phosphorus, the radioactive byproducts formed during production can be detrimental to the environment. It's a race of reproductive growth that is faster with more phosphates (up to a limit determined by sunlight and temperature) vs. killing by chlorine. Your kidneys are the primary regulators of phosphorus balance in your body but many medical conditions can affect your phosphorus level. Any sort of bleeding can be easily cured by turning to phosphorus as a homeopathic remedy. Because phosphorus is not as tightly regulated by the body as calcium, phosphate levels in your blood can rise slightly with a high phosphorus diet, especially after meals. So what does high phosphorus mean for my body?You get hardening of the arteries all over your body, you may get very serious skin ulcers, and your bones get soft. Nitrates are similar. A build up of phosphorus can be dangerous to your health. In addition, for every 1 mg/dL increase in phosphorus there is a 62% higher chance of death. Applying high levels of quick- release nitrogen can burn the roots when applied to the soil and can burn the foliage when applied as a foliar spray or drench. High levels of phosphorus and calcium in the blood can also cause itchy skin and red eyes. Drugs that bind with phosphate, such as sevelamer, lanthanum, and calcium compounds, should be taken with meals as prescribed by a doctor. This can call for additional nitrogen because nitrogen is bound up in the organic matter. This site complies with the HONcode standard for trustworthy health information: verify here. R2R Supporter. "The rate of chlorine kill is the same [with high phosphates], but the rate of growth can be slower with low phosphates. Nutrients come from many sources: fertilizers, automobiles, sewage, manure, and others. You can benefit from the alkaline diet; this diet is also called as alkaline acid diet or alkaline ash diet. Attracts honey eaters. Measurement of phosphate levels in the blood. Although there are no specific signs directly attributable to the condition, symptoms will depend on the underlying cause of hyperphosphatemia. I have a 5 … Antacids such as Tums, are used as effective binders to prevent phosphorus absorption by combining with the phosphorus in CKD patients' intestinal tract. These drugs make phosphate harder to absorb, and more phosphate is excreted. If you put too much on your lawn you will burn the grass – which is just another way of saying you killed your grass. However, in people with severe kidney dysfunction, calcium combines with phosphate, which lowers calcium levels in the blood (a disorder called hypocalcemia). Phosphorus is a very widely distributed element—12th most abundant in crustEarth’s, to which it contributes about 0.10 weight percent. Joined Sep 8, 2015 Messages 6,515 Reaction score 6,464. I am curious to know how much phosphate can actually kill my tank? When you apply soluble phosphorus fertilizers, such as super phosphate, to the soil, chemical reactions cause this readily available phosphorus to revert to … Hyperphosphatemia can affect both dogs and cats. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world. Having too much potassium in your blood can be dangerous. Additionally, dogs with bone diseases and calcium deficiency are susceptible to hyperphosphatemia. AndysReef said: Some of you may know that recently I lost a pair of clownfish a few days ago. The link you have selected will take you to a third-party website. The roasted seeds of pumpkin and squash without salt provides 1174 mg of phosphorus per 100 gram. Hence, managing phosphorus is crucial to a Dialysis patient's health outco. Lawn grasses, such as St. Augustine, are particularly sus- ceptible to iron and zinc defi-ciencies because grasses need high levels of iron and have shallow root systems. This can lead to dangerously high levels of phosphorus in the blood. However, as long as phosphate levels are below 100 ppb and you're maintaining proper pH, water level, chlorine level, and total alkalinity, algae growth shouldn't be a problem. High phosphorus usually causes itching of the skin. Most importantly, high phosphorus can kill Chronic Kidney Disease and Dialysis patients, suggested Fresenius Medical Care Inc. Most of what is known about the health effects of breathing this compound is from studies of workers. I checked my phosphate and it was at .25. You describe using lots of soil coverings which may contribute to higher amounts of organic matter in the soil. Phosphorus (P) is a big part of cannabis growth cycle and plants use phosphorus the most at the seedling and flowering stages of its growth. Regular blood tests will show if the phosphorus level in their blood is too high or too low. High potassium and phosphorus levels doesn't mean you have low nitrogen. An excess of nutrients tends to speed up the growth of algae and diminish the availability of dissolved oxygen. Last full review/revision Apr 2020| Content last modified Apr 2020. R2R Excellence Award. As the matter breaks down, nitrogen is made available to the plants. H People with kidney disease can work with a renal dietitian and their doctor to keep their phosphorus level in balance. Too much phosphate can be toxic. The high phosphorus gets into the skin and can also cause ulcers. Second only to calcium, phosphorous is the most plentiful mineral in your body, and it is necessary for such processes as the production and storage of energy. Regular blood tests will show if the phosphorus level in their blood is too high or too low. The legacy of this great resource continues as the MSD Manual outside of North America. Its high chemical reactivity assures that it does not occur in the free state (except in a … In healthy individuals, the kidneys excrete excess phosphorus with the help of various endocrine hormones, so high phosphorus levels are not a concern. Phosphorus buildup is caused by excessive use of in-organic fertilizer or the use of composts and manures high in phosphorus. If you have a kidney condition like chronic kidney disease, you may have high levels of phosphorus. phosphorus. Mushroom compost should be avoided as it raises soil pH and can kill soil bacteria. Share on Pinterest Kidney disease and diabetes are common causes of hyperphosphatemia. This can lead to itching, brittle bones, painful sores which may not heal, Calcification (stiff or less flexible veins and arteries), heart attack, stroke, hospitalizations, and even death. Learn more about our commitment to Global Medical Knowledge. Phosphorus is an essential dietary nutrient that is concentrated in your bones and cells. The calcium and phosphate also can form crystals (calcify) in body tissue, including within the walls of the blood vessels. Phosphate is one of the body's electrolytes, which are minerals that carry an electric charge when dissolved in body fluids such as blood, but the majority of phosphate in the body is uncharged. Phosphorus is an essential element for plant life, but when there is too much of it in water, it can speed up eutrophication (a reduction in dissolved oxygen in water bodies caused by an increase of mineral and organic nutrients) of rivers and lakes. By exfoliating layered black phosphorus using the same method applied to obtain graphene from graphite, 2D black phosphorus … Causes calciphylaxis. Without mycorrhizal fungi, plants need to expend more energy making larger root systems. Most people with hyperphosphatemia do not have symptoms. That is why you should take your binders when you start to eat, not after you eat. You can actually kill a tree if you apply too much fertilizer. Recommended Reading: Over Forty Popular Beverages Outside Of Cola Contain Dangerous Phosphorus Levels For CKD Patients. This can lead to algal blooms in water, which can kill fish and other plants. Cuttlefish, a mollusk related to … Seafood. When there is an increase or decrease in the value about the stated numbers, the individual suffering from chronic kidney disease can seek assistance from a dietician who will perform a series of tests to find out the accurate value of the phosphorus content. These seeds are consumed in 5 ways, they are whole seeds, roasted with salt or without salt. Virilization is the development of exaggerated masculine characteristics, usually in women, often as a result of the adrenal glands overproducing androgens (male hormones). Both iron and zinc deficiencies occur in the youngest tissues and can occur at the same time, which … If you would like to learn more about how the condition affects cats, please visit this page in the PetMD health library. The reports also show that the cancer cells produce an acidic environment due to a high-metabolic-rate. Phosphorus can be found in cannabis anywhere from 0.1% to 0.5% of the overall weight. As a rule of thumb we generally discourage using manures and compost around natives as it is difficult to attain how much nutrient will be released. © 2020 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA), © 2020 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA, Athletes taking large doses of androgens to increase muscle bulk, Overuse of erectile dysfunction medications by men. While phosphorus levels great than 5.5 are a serious problem. A:Phosphorus is an important element, which is required for strengthening bones and for the normal functioning of cells & energy metabolism.Most of the phosphorous in the body (~90%) is present in the bone. The desired level of phosphorus is 3.5 – 5.5. Damage to the blood vessels of the mouth has been observed in rats breathing air containing white phosphorus. Even when Chronic Kidney Disease (CKD) patients limit foods that are high in phosphorus, most still find themselves with high phosphorus levels. In these people, the kidneys do not excrete enough phosphate. Phosphorus is an essential component in soil but if you put to much it can kill the plant in the soil. Not only does excessive phosphorous harm plants, it can also stay in your soil for years. The level of phosphorus in your blood will help determine if you are eating too many high phosphorus foods and if you need to be on medication to help control the phosphorus level in your blood. Hyperphosphatemia is rare except in people with severe kidney dysfunction. Zinc deficiencies show a bleaching of the tissue. Thanks . High soil phospho-rus levels also can threaten streams, rivers, lakes and oceans. Whether you need a pond high in productivity or prefer a pond that's clear, it's important to understand that phosphorus is the key to management in most scenarios. The symptoms of high potassium are usually none. What is the goal for my phosphorus level?In patients on dialysis, we want to keep your phosphorus level below 5.5 mg/dl. The calcium and phosphate also can form crystals (calcify) in body tissue, including within the walls of the blood vessels. Foods that are high in phosphate, such as milk, egg yolks, chocolate, and soft drinks, should be avoided. The amount of phosphorus found in these seeds can be as high as 1233 mg per 100 gram. However, getting too much phosphorus can be … Hyperphosphatemia is when you have too much phosphate in your blood. Phosphorus Fertilizers – applying a fertilizer with a high phosphorous content in the NPK ratio (example: 10-20-10, ... you can see it’s fairly simple to ensure you have a balanced amount of phosphorous in soil. So why call phosphorus a killer?Because hardening of the arteries, either to your heart or the rest of your body, is the number one killer of people on dialysis, or even with people who aren't yet on dialysis but have kidney disease. Second, as the calcium leaves the blood system with the phosphorus, the lower calcium amount in your blood causes a hormone called PTH to be released, which take the calcium out of your bones to keep the calcium normal in the bloodstream. Shallow-rooted annual and perennial plants frequently have iron and zinc deficiencies caused by excessive phosphorus. I am not noticing the phosphorus levels say 6.5 high from a range of 2.5-6.0. The safe level of phosphorus content of the body is 2.5 to 4.5 mg/dL. Symptoms and Types. Phosphorus can be found in a wide variety of foods, from dairy to whole grains. Phosphorus is a very widely distributed element—12th most abundant in crustEarth’s, to which it contributes about 0.10 weight percent. Soft drinks and pre-packaged food items are high in phosphorus content, which some nutritionists believe contributes to over-consumption of phosphorus. Also, acid loving plants grown in neutral to alkaline soils display symptoms of deficiencies. What is high phosphorus (hyperphosphatemia)? While Dialysis Treatments remove some phosphorus from the body, it cannot replace the kidneys and patients are at constant risk of high phosphorus (Hyperphosphatemia). Low calcium can cause muscle cramps and spasms but also causes an increase in parathyroid hormone levels, resulting in bone weakness and other problems. Many types of seafood are good sources of phosphorus. In hyperphosphatemia, the level of phosphate in blood is too high. Phosphorus is an essential dietary nutrient that is concentrated in your bones and cells. Phosphate levels are normally higher in children than in adults because their bones are actively growing. You are unable tot excrete the phosphorus that you take in with your food, which is food in protein-containing items, such as dairy products and meats. But just choosing the right foods isn't the only dietary approach to managing your condition. Low phosphate levels in children can inhibit bone growth and high levels may be an indication of a condition that disrupts the body's balance of minerals. … If you don’t get enough phosphorus, symptoms of a deficiency can include anxiety, decreased appetite, irritability, breathing difficulty, laziness, and changes to mood. Sevelamer and lanthanum are often used for people undergoing dialysis because calcium compounds can make calcium-phosphate crystals more likely to form in tissues. Over time this can create bonelike crystals. Once your phosphorus level goes below 5.5 mg/dL on a regular basis, your dietitian may be able to help you safely include an occasional high-phosphorus food into your kidney diet . Occasionally, the only symptom of high blood potassium is a sudden heart arrhythmia that can result in heart attack. As long as we get around 700mg of phosphorus on a daily basis, experts say that we should be fine. Its cosmic abundance is about one atom per 100 atoms of silicon, the standard. And if the fertilizer contains too much potassium and phosphorus, it creates excessive soil salts that trees may be unable to tolerate. Abnormally high or low levels may cause serious metabolic problems. But the truth is, we don’t know at this stage what the long-term impact of greywater use on gardens will be. The legacy of this great resource continues as the MSD Manual outside of North America. Please confirm that you are not located inside the Russian Federation. What is a normal phosphorus level in the body?If your kidneys were working, your kidneys would excrete the phosphorus and keep your blood levels at 2.5-4.5 mg/dl. Mar 1, 2017 #2 reeferfoxx 5000 Club Member View Badges. “Eating too much cheese with its high saturated fat and salt content can contribute to high blood pressure,” he adds. Why can't I eat high phosphorus-containing foods?Since your kidneys don't excrete phosphorus, the phosphorus you take into your body when eating is not excreted. High-phosphorus fertiliser will kill Gungurru Eucalyptus caesia ‘caesia’ Short Narrow Medium WA Yes No Spring No No Evergreen Daintier, more 'tree-like' version of the Silver Princess. Phosphorus is another first aid kit must have. High phosphorus can be particularly dangerous for the heart. As you now know, phosphorus enters your pond on the sly through fish and fish food, plants and fertilizers, runoff, rain, and even geese. High phosphorus can lead to calciphylaxis. Less energy is then available for growing, flowering and fruiting. Every ion in fertilizer is both a food source for plants at low levels and a toxin at high levels. High phosphorus can cause the formation and deposit of a calcium and phosphorus structure in your veins and organs. It can also be quite useful for other symptoms that may be associated with either anxiety or … Since your kidneys don't excrete phosphorus, the phosphorus you take into your body when eating is not excreted. LisaAnn . High phosphorous levels in your soil are usually the culprit of over-fertilizing or adding too much manure. To keep phosphorus at the correct level, you may need to take a phosphate binder (i.e. Not only does excessive phosphorous harm plants, it can also stay in your soil for years. The vet never mentioned anything was wrong with her on th chart it says "insignificant". Phosphorus is an essential mineral your body needs for maintaining healthy bones, cell membranes and energy production, but overconsuming phosphorus can cause high serum levels of phosphate, also known as hyperphosphatemia, especially in people with kidney problems. People with kidney disease can work with a renal dietitian and their doctor to keep their phosphorus level in balance. Dialysis, often used to treat kidney dysfunction, is not very effective at removing phosphate and thus does not reduce the risk of hyperphosphatemia.
2020 can high phosphorus kill you